Wednesday, 15 March 2017

Pharmaceutical Formulations 2018

ConferenceSeries Ltd is a renowned organization that organizes highly notable pharmaceutical conferences throughout the globe. Currently we are bringing forth “15th International Conference and Exhibition on Pharmaceutical Formulations” (Formulation 2018) scheduled to be held during July 26-27, 2018 at Rome, Italy. The conference invites all the participants across the globe to attend and share their insights and convey recent developments in the field of Pharmaceutical Formulations.
ConferenceSeries Ltd organizes a conference series of 1000+ Global Events inclusive of 1000+ Conferences, 1000+ Upcoming and Previous Symposiums and Workshops in USA, Europe & Asia with support from 1000 more scientific societies and publishes 700+ Open
Pharmaceutical formulation is defined as the process in which different chemical substances are combined to produce a final medicinal product. Since 1991, we have been designing Liquid, Suspension, Powder, Solid solution, Semisolid formulations and even drug eluting devices.The formulation studies involve developing a preparation of drug acceptable for patient. Pharmaceutical Formulation is the word often used in a way that includes dosage form. Formulation studies consider factors such as solubility, particle size, polymorphism and pH as all of these can influence bioavailability and hence the activity of a drug.
Solid dosage formulations are important dosage forms in pharmaceuticals. e.g. tablets, capsules, granules, sachets, reconstitutable powders, powders, dry powder inhalers and chewables. Solid dosage form contains unit dose of one or more medicament. Easy to package and carry around, solid dosage forms are also difficult to tamper with, stable and easy to dose accurately – approximately 80% of errors in medication are associated with the use of liquid formulations. Excipients include Binders, Glidants, Sweeteners etc.,
Semi solid dosage forms are the products when applied to the skin treat a pathological condition and protects from other harmful environment. They are smooth,non-staining and get miscible with skin secretions. Creams, Gels, Pastes etc. are the examples. Semisolid dosage forms usually are intended for localized drug delivery. In the past few years, however, these forms also have been explored for the systemic delivery of various drugs. Semisolid dosage forms for dermatological drug therapy are intended to produce desired therapeutic action at specific sites in the epidermal tissue.
Liquid dosage forms are essential Pharmaceutical products which involves a mixture of active drug componentsand nondrug components (excipients). Liquid dosage forms are prepared: a) by dissolving the active drug substance in an aqueous or non- aqueous (e.g. glycerin, ether, alcohol) solvent b) By suspending the drug in appropriate medium or c) By incorporating the drug substance into an oil or water phase. Ex: Suspension, Emulsion, Syrups, Elixers
Gaseous dosage forms are packed in a container which gets released upon applying pressure. The gas inside contains therapeutically active medicaments. The containers have valve systems with continuous or limited delivery. They are used for topical application on skin and as local application into nose and mouth. Ex: Nebulizer, Sprays, Inhalers., April 11-13, 2017 Seoul, South Korea.
Formulations are classified into two types: based on Route of administration and Physical form. Based on route of administration they are classified as Oral, Topical, Rectal, Parenteral, Vaginal, Inhaled, Ophthalmic and octic. Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patient. For orally administered drugs, this usually involves incorporating the drug into a tablet or a capsule. It is important to make the distinction that a tablet contains a variety of other potentially inert substances apart from the drug itself, and studies have to be carried out to ensure that the encapsulated drug is compatible with these other substances in a way that does not cause harm, whether direct or indirect.
“Novel Drug delivery System (NDDS) refers to the formulations, systems and technologies for transporting a pharmaceutical compound in the body as it is needed to safely achieve its desired therapeutic effectsDrug delivery systems (DDS), are based on approaches that are interdisciplinary and that combine pharmaceutics, bio conjugate chemistry, and molecular biology.
Prior to formulation some physico chemical properties are characterized. Chemical properties include structure, form and reactivity. Physical properties include particle size, melting point and solubility. In case of some drugs biological properties are also characterized. Age and sex of the patient also play a major role in dosage design. The others factors are Solubility, Buffer capacity and partition coefficient.
The drug subjected to drug development undergoes number of trials and are screened at different stages to produce a final potent drug for the treatment of various diseases. During this process different properties are checked to see whether the drug is non-toxic to living system and is therapeutic or not. Using suitable excipients and technological preparations the active substances are formulated into final dosage form. The final product is the Actual composition of preparation, manufacturing specification.

Pharmaceutical excipients are those substances other than the prodrug which are included in the manufacturing process or are contained in a finished pharmaceutical product dosage form. There are many excipients. Few of them include Antiadherents, Binders, Coatings, Colors, Flavours, Lubricants, Preservatives, Sweeteners etc. Excipients are crucial to drug delivery within the body. Generally, an excipient has no medicinal properties. Its standard purpose is to streamline the manufacture of the drug product and ultimately facilitate physiological absorption of the drug.

Drug design, also known as rational drug design, is the inventive process of finding new medications based on the knowledge of a biological target. Drug design defines the design of molecules that are complementary in shape and charge to the bimolecular target with which they interact and therefore will bind to it. Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.
Pharmaceutical analysis is a branch of practical chemistry that involves a series of process for qualification, purification, identification and determination of a substance, separation of the components of a solution or mixture, or determination of structure of chemical compounds. The sample to be analysed is called as analyse. Pharmaceutical Analysis is an Analytical Method used to determination the quality and quantity of the pharmaceutical products. It also gives the information about the purity and safety of the products. Briefly it can be described as it identifies, determines, quantifies, purifies and separates the active compound from the mixture.
The drug product manufacturing facility is designed to produce injectable in syringes or vials in Grade A environment. Industries strive to improve product quality in today’s competitive environment and as well reduce the production cost. Scaling up from our development services to full scale commercial drug product manufacture or transferring existing commercial products we can meet your commercial drug product manufacturing requirements.
Targeted drug delivery sometimes called smart drug delivery is a method of delivering medication to a patient in a manner that increases the concentration of the medication in some parts of the body relative to other parts in the meantime reduce side effects/toxicity of payloads which are key factors for improving patient compliance.
Pharmacists can play a role helping patients with chronic diseases have better medication at correct time and get good clinical outcomes.  They play a key role in immunization services and identifying vaccine candidates. They Participate and maintain a significant role in multidisciplinary patient care rounds. Patients often make their own decisions about managing their medications. Pharmacists could usefully serve as patient advocates, providing information that permits patients to assess risk and enhance their autonomy.
Track 16: Regulatory Affairs
Regulatory affairs are a new profession which is developed by the governments to protect public health. The main aim is controlling the safety and efficacy of products in areas including pharmaceuticals, veterinary medicines, medical devices, pesticides, agrochemicals and cosmetics. Regulatory affairs also have a very specific meaning within the healthcare industries.
Pharma industries are showing increased confidence in the growth of manufacturing in the market. This turn around in the market is due to the potential which is being driven by concerns of quality in some Asian markets and a marketed shift in the drug development. The primary reason behind this is an increased regulatory confidence in the standards of manufacturing.